Note: We recommend using either Chrome or Firefox to browse
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Differential analysis using MSstatsTMT and limmaRMSV000000308.3
Raw data were analyzed with Maestro and the PSM file was exported to R for the downstream statistical analysis. Data processing, protein quantification, and normalization steps were performed using MSstatsTMT v2.2.0. In total, 2,604 proteins were quantified and used for statistical analysis. Various statistical approaches, including MSstatsTMT and limma, are applied to detect changes in abundance In order to see how the unbalanced design impacted the performance of differential analysis, we manually generated an unbalanced design by eliminating a subset of samples from each mixture.
+Homo sapiens (NCBITaxon:9606)
Severe acute respiratory syndrome coronavirus 2 (NCBITaxon:2697049)
+MOD:01720 - "A protein modification that effectively replaces a hydrogen atom of a residue with the Proteome Sciences TMT6plex-126 reporter+balance group."
MOD:00702
MOD:00397 - "A protein modification that is produced by reaction with iodoacetamide, usually replacement of a reactive hydrogen with a methylcarboxamido group."
Oct. 13, 2022, 12:14 AM
0
0
0
33
179.11
2
A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-PurposingMSV000085144 | PXD018117
Open modification searching of SARS-CoV-2-human protein interaction data with MSFraggerRMSV000000309.4 | RPXD018240.4
We performed a reanalysis of a SARS-CoV-2-human protein-protein interaction map from MSV000085144/PXD018117. With open modification searching (OMS) any type of PTM can be identified in an unbiased fashion, without the need to explicitly specify a limited number of variable modifications. This makes it possible to explore the general presence of PTMs in the context of the SARS-CoV-2 virus-host interactome. The reanalysis with ANN-SoLo (RMSV000000359.1) resulted in an over two-fold increase in identified spectra. Based on these identifications, our detected protein interactions showed a high overlap with independent mass spectrometry-based SARS-CoV-2 studies and virus-host interactions for alternative viruses, as well as previously unknown protein interactions. Additionally, we identified several novel modification sites on SARS-CoV-2 proteins that we investigated in relation to their interactions with host proteins. This reanalysis with MSFragger showed a decent overlap with the results from ANN-SoLo, illustrating that our results are not unique to ANN-SoLo and that a similar analysis could also be done with alternative OMS tools. In the original study affinity purification was performed using 27 SARS-CoV-2 proteins that were individually tagged and expressed in triplicate in HEK-293T cells. Bead-bound proteins were denatured, reduced, carbamidomethylated, and enzymatically digested using trypsin, and each sample was injected via an Easy-nLC 1200 (Thermo Fisher Scientific) into a Q-Exactive Plus mass spectrometer (Thermo Fisher Scientific). The SARS-CoV-2 proteins that were included are: all mature nonstructural proteins (Nsps), except for Nsp3 and Nsp16; a mutated version of Nsp5 to disable its proteolytic activity (Nsp5_C145A); and all predicted SARS-CoV-2 open reading frames (Orfs), including the spike (S), membrane (M), nucleocapsid (N), and envelope (E) protein. First, the downloaded raw files were converted to MGF files using ThermoRawFileParser (version 1.2.3). Next, OMS was performed using MSFragger (version 3.5) and FragPipe (version 18.0) against a concatenated FASTA file containing human protein sequences (Uniprot reviewed sequences downloaded on 2020/02/28), the SARS-CoV-2 protein sequences (version 2020/03/05), and the green fluorescent protein sequence. An equal number of decoy protein sequences were generated using FragPipe. The MSFragger search settings included a precursor mass tolerance between -150 Da and 500 Da, a fragment mass tolerance of 0.02 Da, and trypsin cleavage with up to two missed cleavages. Cysteine carbamidomethylation was used as a fixed modification, and oxidation of methionine and N-terminal acetylation were used as variable modifications. Other search settings were kept at their default values. PSMs were processed using PeptideProphet (version 4.4.0) with the FragPipe default settings for open searches and filtered at 1% FDR.
+Homo sapiens (NCBITaxon:9606)
Severe acute respiratory syndrome coronavirus 2 (NCBITaxon:2697049)
+SARS-CoV-2
coronavirus
COVID-19
PPI
CoronaMassKB
0
0
0
0
0
Charlotte Adams (CAdams)
Exactive Plus
MS:1002864 - No post-translational-modifications are included in the identified peptides of this dataset
Sep. 12, 2022, 6:20 AM
0
0
0
3
172.44
3
A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-PurposingMSV000085144 | PXD018117
Open modification searching of SARS-CoV-2-human protein interaction data reveals novel viral modification sitesRMSV000000359.1
We performed a reanalysis of a SARS-CoV-2-human protein-protein interaction map from MSV000085144/PXD018117. Open modification searching was used to investigate the presence of PTMs in the context of the SARS-CoV-2 virus-host PPI network. Based on an over two-fold increase in identified spectra, our detected protein interactions show a high overlap with independent mass spectrometry-based SARS-CoV-2 studies and virus-host interactions for alternative viruses, as well as previously unknown protein interactions. Additionally, we identified several novel modification sites on SARS-CoV-2 proteins that we investigated in relation to their interactions with host proteins. A detailed analysis of relevant modifications, including phosphorylation, ubiquitination, and S-nitrosylation, provides important hypotheses about the functional role of these modifications during viral infection by SARS-CoV-2. In the original study affinity purification was performed using 27 SARS-CoV-2 proteins that were individually tagged and expressed in triplicate in HEK-293T cells. Bead-bound proteins were denatured, reduced, carbamidomethylated, and enzymatically digested using trypsin, and each sample was injected via an Easy-nLC 1200 (Thermo Fisher Scientific) into a Q-Exactive Plus mass spectrometer (Thermo Fisher Scientific). The SARS-CoV-2 proteins that were included are: all mature nonstructural proteins (Nsps), except for Nsp3 and Nsp16; a mutated version of Nsp5 to disable its proteolytic activity (Nsp5_C145A); and all predicted SARS-CoV-2 open reading frames (Orfs), including the spike (S), membrane (M), nucleocapsid (N), and envelope (E) protein. First, the downloaded raw files were converted to MGF files using ThermoRawFileParser (version 1.2.3). Next, OMS was performed using the ANN-SoLo spectral library search engine (version 0.2.4). A combined human-SARS-CoV-2 spectral library was used for searching. The MassIVE-KB library (version 2018/06/15) was used as human spectral library. SARS-CoV-2 spectra were simulated by generating all possible tryptic peptide sequences from the SARS-CoV-2 protein sequences downloaded from UniProt (version 2020/03/05) using Pyteomics (version 4.3.2) and predicting the corresponding spectra using Prosit (version prosit_intensity_2020_hcd; collision energy 33 as determined by Prosit collision energy calibration). A simulated spectral library for the green fluorescent protein was generated in a similar fashion. A final spectral library was compiled by merging all spectra using SpectraST (version 5.0) and adding decoy spectra in a 1:1 ratio using the shuffle-and-reposition method. ANN-SoLo was configured to use a 20 ppm precursor mass tolerance during the first step of its cascade search and a 500 Da precursor mass tolerance during its open search. Other search settings were to filter peaks below 101 m/z, above 1500 m/z, and in a 0.5 m/z window around the precursor mass; a 0.02 m/z fragment mass tolerance; and a bin size of 0.05 m/z. The remaining settings were kept at their default values. Peptide-spectrum matches (PSMs) were filtered at 1% FDR.
+Homo sapiens (NCBITaxon:9606)
Severe acute respiratory syndrome coronavirus 2 (NCBITaxon:2697049)
Human Calu-3 cell proteome response to a wild type infectious clone of H7N9 and mutant H7N9 viruses MSV000079164 | PXD002385
Human Calu-3 cell proteome response to Middle Eastern Respiratory Syndrome (icMERS) coronavirusMSV000080025 | PXD004716
Calu-3 cell proteome response to H1N1 virusMSV000080026
CoronaMassKB Hackathon: MassIVE/CCMS MSStats on Maestro/ MaxQuant reanalysis of MSV000080026, MSV000079164 / PXD002385, MSV000080025 / PXD004716 Calu-3 response to H1N1, H7N9 and MERS viral infectionRMSV000000320.2
CoronaMassKB Hackathon: Early-access community reanalysis of mass spectrometry data. MassIVE/CCMS MSStats on Maestro/ MaxQuant reanalysis of MSV000080026, MSV000079164 / PXD002385, MSV000080025 / PXD004716 Calu-3 response to H1N1, H7N9 and MERS viral infection
+Homo sapiens (NCBITaxon:9606)
Middle East respiratory syndrome-related coronavirus (NCBITaxon:1335626)
Influenza A virus (A/Wilson-Smith/1933(H1N1)) (NCBITaxon:381518)
A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-PurposingMSV000085144 | PXD018117
CoronaMassKB Hackathon: MassIVE/CCMS MSStats on Maestro/ MaxQuant reanalysis of MSV000085144 / PXD018117 A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-PurposingRMSV000000316.3
CoronaMassKB Hackathon: Early-access community reanalysis of mass spectrometry data. MassIVE/CCMS MSStats on Maestro/ MaxQuant reanalysis of MSV000085144 / PXD018117 A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Purposing
+Homo sapiens (NCBITaxon:9606)
Severe acute respiratory syndrome coronavirus 2 (NCBITaxon:2697049)
Inhibition of growth factor signaling prevents SARS-CoV-2 replicationMSV000085494 | PXD018357
CoronaMassKB Hackathon: MassIVE/CCMS MSStats on MS-GF+ reanalysis of MSV000085494 / PXD018357 Inhibition of growth factor signaling prevents SARS-CoV-2 replication, Non-phospho files onlyRMSV000000341.4 | RPXD025723.4
CoronaMassKB Hackathon: Early-access community reanalysis of mass spectrometry data. MassIVE/CCMS MSStats on MS-GF+ reanalysis of MSV000085494 / PXD018357 Inhibition of growth factor signaling prevents SARS-CoV-2 replication, Non-phospho files only
+Homo sapiens (NCBITaxon:9606)
Severe acute respiratory syndrome coronavirus 2 (NCBITaxon:2697049)
Inhibition of growth factor signaling prevents SARS-CoV-2 replicationMSV000085494 | PXD018357
CoronaMassKB Hackathon: MassIVE/CCMS MSStats on MS-GF+ reanalysis of MSV000085494 / PXD018357 Inhibition of growth factor signaling prevents SARS-CoV-2 replication, Phospho files onlyRMSV000000341.3 | RPXD025723.3
CoronaMassKB Hackathon: Early-access community reanalysis of mass spectrometry data. MassIVE/CCMS MSStats on MS-GF+ reanalysis of MSV000085494 / PXD018357 Inhibition of growth factor signaling prevents SARS-CoV-2 replication, Phospho files only
+Homo sapiens (NCBITaxon:9606)
Severe acute respiratory syndrome coronavirus 2 (NCBITaxon:2697049)
Primary human fibroblasts proteome response to an icMERS coronavirusMSV000079701 | PXD004100
Primary human fibroblasts proteome response to an icMERS coronavirusMSV000080028 | PXD004718
Primary human fibroblasts Proteome response to an icMERS coronavirusMSV000081887
CoronaMassKB Hackathon: MassIVE/CCMS MSStats on Maestro/ MaxQuant reanalysis of MSV000079701 / PXD004100, MSV000080028 / PXD004718, MSV000081887 Primary human fibroblasts proteome response to an icMERS coronavirusRMSV000000321.3
CoronaMassKB Hackathon: Early-access community reanalysis of mass spectrometry data. MassIVE/CCMS MSStats on Maestro/ MaxQuant reanalysis of MSV000079701 / PXD004100, MSV000080028 / PXD004718, MSV000081887 Primary human fibroblasts proteome response to an icMERS coronavirus
+Homo sapiens (NCBITaxon:9606)
Middle East respiratory syndrome-related coronavirus (NCBITaxon:1335626)
CoronaMassKB Hackathon: MassIVE/CCMS MSStats on Maestro/ MaxQuant reanalysis of MSV000085516 / PXD018970 Urine proteomics profiling of the COVID-19RMSV000000343.1 | RPXD025724.1
CoronaMassKB Hackathon: Early-access community reanalysis of mass spectrometry data. MSStats on Maestro/ MaxQuant reanalysis of MSV000085516 / PXD018970 Urine proteomics profiling of the COVID-19
+Homo sapiens (NCBITaxon:9606)
Severe acute respiratory syndrome coronavirus 2 (NCBITaxon:2697049)
Inhibition of growth factor signaling prevents SARS-CoV-2 replicationMSV000085494 | PXD018357
CoronaMassKB Hackathon: MassIVE/CCMS MSStats on Maestro reanalysis of MSV000085494 / PXD018357 Inhibition of growth factor signaling prevents SARS-CoV-2 replication (Non-phospho files only)RMSV000000341.2 | RPXD025723.2
CoronaMassKB Hackathon: Early-access community reanalysis of mass spectrometry data. MassIVE/CCMS MSStats on Maestro reanalysis of MSV000085494 / PXD018357 Inhibition of growth factor signaling prevents SARS-CoV-2 replication (Non-phospho files only)
+Homo sapiens (NCBITaxon:9606)
Severe acute respiratory syndrome coronavirus 2 (NCBITaxon:2697049)
Primary human microvascular endothelial cells proteome response to an icMERS coronavirusMSV000079703 | PXD004101
Primary human microvascular endothelial cells proteome response to an icMERS coronavirusMSV000080029 | PXD004719
Primary human microvascular endothelial cells Proteome response to an icMERS coronavirusMSV000081888
CoronaMassKB Hackathon: MassIVE/CCMS MSStats on Maestro/ MaxQuant reanalysis of MSV000079703 / PXD004101, MSV000080029 / PXD004719, MSV000081888 Primary human microvascular endothelial cells Proteome response to an icMERS coronavirusRMSV000000322.3
CoronaMassKB Hackathon: Early-access community reanalysis of mass spectrometry data. MassIVE/CCMS MSStats on Maestro/ MaxQuant reanalysis of MSV000079703 / PXD004101, MSV000080029 / PXD004719, MSV000081888 Primary human microvascular endothelial cells Proteome response to an icMERS coronavirus
+Homo sapiens (NCBITaxon:9606)
Middle East respiratory syndrome-related coronavirus (NCBITaxon:1335626)
GNPS - Primary human airway epithelial cells proteome response to an icMERS coronavirusMSV000083529
GNPS - Primary human airway epithelial cells proteome response to an icMERS coronavirusMSV000083530
GNPS - Primary human airway epithelial cells proteome response to an icMERS coronavirusMSV000083531
CoronaMassKB Hackathon: MassIVE/CCMS MSStats on Maestro/ MaxQuant reanalysis of MSV000083529, MSV000083530, MSV000083531 Primary human airway epithelial cells proteome response to an icMERS coronavirusRMSV000000342.1
CoronaMassKB Hackathon: Early-access community reanalysis of mass spectrometry data. MassIVE/CCMS MSStats on Maestro/ MaxQuant reanalysis of MSV000083529, MSV000083530, MSV000083531 Primary human airway epithelial cells proteome response to an icMERS coronavirus
+Homo sapiens (NCBITaxon:9606)
Middle East respiratory syndrome-related coronavirus (NCBITaxon:1335626)
Human Calu-3 cell proteome response to Middle Eastern Respiratory Syndrome (icMERS) coronavirusMSV000080025 | PXD004716
CoronaMassKB Hackathon: MassIVE/CCMS MSStats on Maestro /MaxQuant reanalysis of MSV000080025 / PXD004716 Human Calu-3 cell proteome response to Middle Eastern Respiratory Syndrome (icMERS) coronavirusRMSV000000319.3
CoronaMassKB Hackathon: Early-access community reanalysis of mass spectrometry data. MassIVE/CCMS MSStats on Maestro /MaxQuant reanalysis of MSV000080025 / PXD004716 Human Calu-3 cell proteome response to Middle Eastern Respiratory Syndrome (icMERS) coronavirus
+Homo sapiens (NCBITaxon:9606)
Middle East respiratory syndrome-related coronavirus (NCBITaxon:1335626)
Calu-3 cell proteome response to H1N1 virusMSV000080026
CoronaMassKB Hackathon: MassIVE/CCMS MSStats on Maestro/ MaxQuant reanalysis of MSV000080026 Calu-3 cell proteome response to H1N1 virusRMSV000000317.3
CoronaMassKB Hackathon: Early-access community reanalysis of mass spectrometry data. MassIVE/CCMS MSStats on Maestro/MaxQuant reanalysis of MSV000080026 Calu-3 cell proteome response to H1N1 virus
+Homo sapiens (NCBITaxon:9606)
Influenza A virus (A/Wilson-Smith/1933(H1N1)) (NCBITaxon:381518)
Shotgun proteomics of Vero E6 cells infected by Italy-INMI1 SARS-CoV-2 virusMSV000085510 | PXD018594
CoronaMassKB Hackathon: MassIVE/CCMS MSStats on Maestro/ MaxQuant reanalysis of MSV000085510 / PXD018594 Shotgun proteomics of Vero E6 cells infected by Italy-INMI1 SARS-CoV-2 virusRMSV000000340.1 | RPXD025722.1
CoronaMassKB Hackathon: Early-access community reanalysis of mass spectrometry data. MassIVE/CCMS MSStats on Maestro/ MaxQuant reanalysis of MSV000085510 / PXD018594 Shotgun proteomics of Vero E6 cells infected by Italy-INMI1 SARS-CoV-2 virus
+Betacoronavirus sp. (NCBITaxon:1928434)
Chlorocebus aethiops aethiops (NCBITaxon:101841)
Severe acute respiratory syndrome coronavirus 2 (NCBITaxon:2697049)
GNPS - Proteomic and Metabolomic Characterization of COVID-19 Patient SeraMSV000085507 | PXD019221
CoronaMassKB Hackathon: MassIVE/CCMS MSStats on Maestro reanalysis of MSV000085507 / PXD019221 Proteomic and Metabolomic Characterization of COVID-19 Patient SeraRMSV000000331.3
CoronaMassKB Hackathon: Early-access community reanalysis of mass spectrometry data. MassIVE/CCMS MSStats on Maestro reanalysis of MSV000085507 / PXD019221 Proteomic and Metabolomic Characterization of COVID-19 Patient Sera
+Homo sapiens (NCBITaxon:9606)
Severe acute respiratory syndrome coronavirus 2 (NCBITaxon:2697049)
CoronaMassKB hackathon: MassIVE/CCMS MSStats on Maestro reanalysis of MSV000085349 / PXD018581 Proteomics of SARS-CoV and SARS-CoV-2 infected cells, Non-phospho files onlyRMSV000000313.4
CoronaMassKB hackathon: Early-access community reanalysis of mass spectrometry data. MassIVE/CCMS MSStats on Maestro reanalysis of MSV000085349 / PXD018581 Proteomics of SARS-CoV and SARS-CoV-2 infected cells
+Homo sapiens (NCBITaxon:9606)
Severe acute respiratory syndrome-related coronavirus (NCBITaxon:694009)
Severe acute respiratory syndrome coronavirus 2 (NCBITaxon:2697049)
Inhibition of growth factor signaling prevents SARS-CoV-2 replicationMSV000085494 | PXD018357
CoronaMassKB Hackathon: MassIVE/CCMS MSStats on Maestro reanalysis of MSV000085494 / PXD018357 Inhibition of growth factor signaling prevents SARS-CoV-2 replication (Phospho files only)RMSV000000341.1 | RPXD025723.1
CoronaMassKB Hackathon: Early-access community reanalysis of mass spectrometry data. MassIVE/CCMS MSStats on Maestro reanalysis of MSV000085494 / PXD018357 Inhibition of growth factor signaling prevents SARS-CoV-2 replication (Phospho files only)
+Homo sapiens (NCBITaxon:9606)
Severe acute respiratory syndrome coronavirus 2 (NCBITaxon:2697049)
Identification results for the end-to-end PPI reanalysis described in the following Jupyter notebook: https://github.com/bittremieux/sars_cov_2
+Homo sapiens (NCBITaxon:9606)
Severe acute respiratory syndrome coronavirus 2 (NCBITaxon:2697049)
+SARS-CoV-2
coronavirus
COVID-19
PPI
CoronaMassKB
0
0
0
0
0
Wout Bittremieux (woutb)
MS:1002526
MS:1002864 - No post-translational-modifications are included in the identified peptides of this dataset
Sep. 29, 2020, 1:54 PM
0
0
0
102
382.15
21
GNPS - Proteomic and Metabolomic Characterization of COVID-19 Patient SeraMSV000085507 | PXD019221
CoronaMassKB Hackathon: MassIVE/CCMS MSStats on MS-GF+ reanalysis of MSV000085507 / PXD019221 Proteomic and Metabolomic Characterization of COVID-19 Patient SeraRMSV000000331.2
CoronaMassKB Hackathon: Early-access community reanalysis of mass spectrometry data. MassIVE/CCMS MSStats on MS-GF+ reanalysis of MSV000085507 / PXD019221 Proteomic and Metabolomic Characterization of COVID-19 Patient Sera
+Homo sapiens (NCBITaxon:9606)
Severe acute respiratory syndrome coronavirus 2 (NCBITaxon:2697049)
GNPS - Proteomic and Metabolomic Characterization of COVID-19 Patient SeraMSV000085507 | PXD019221
CoronaMassKB Hackathon: MassIVE/CCMS Maestro reanalysis of MSV000085507 / PXD019221 Proteomic and Metabolomic Characterization of COVID-19 Patient SeraRMSV000000331.1
CoronaMassKB Hackathon: Early-access community reanalysis of mass spectrometry data. MassIVE/CCMS Maestro reanalysis of MSV000085507 / PXD019221 Proteomic and Metabolomic Characterization of COVID-19 Patient Sera
+Homo sapiens (NCBITaxon:9606)
Severe acute respiratory syndrome coronavirus 2 (NCBITaxon:2697049)
This reanalysis is the statistical analysis results from the original manuscript. The raw spectra were analyzed by Proteome Discoverer 2.4.1.15. The protein report includes peptide abundance, protein abundance, and significant statistical testing results which were measured on the training cohort (17 replicates from 17 Healthy patients, 19 replicates from 18 non-COVID-19 patients, 20 replicates from 18 non-severe COVID-19 patients and 14 replicates from 13 severe COVID-19 patients). Log2 fold change (log2 FC) was calculated on the mean of the same patient group for each pair of comparing groups. Two-sided unpaired Welch's t-test was performed for each pair of comparing groups and adjusted p values were calculated using Benjamini & Hochberg correction.
+Homo sapiens (NCBITaxon:9606)
Severe acute respiratory syndrome coronavirus 2 (NCBITaxon:2697049)
The same PSM report from Proteome Discoverer 2.4.1.15 (Thermo Fisher Scientific) in RMSV000000327.3 was used for this reanalysis. For statistical analysis, data preprocessing, multiple fractions combination, data normalization with reference channel, protein summarization, and statistical testing using MSstatsTMT v1.6.2 was performed. The PSM report measures the training cohort described in the original manuscript, which includes 17 replicates from 17 Healthy patients, 19 replicates from 18 non-COVID-19 patients, 20 replicates from 18 non-severe COVID-19 patients and 14 replicates from 13 severe COVID-19 patients. The remaining 20 replicates are not used for this reanalysis and thus were labeled as "Empty" condition. R script for MSstatsTMT analysis is available in the 'methods' folder (FTP download -> methods).
+Homo sapiens (NCBITaxon:9606)
Severe acute respiratory syndrome coronavirus 2 (NCBITaxon:2697049)
Primary human microvascular endothelial cells proteome response to an icMERS coronavirusMSV000079703 | PXD004101
Primary human microvascular endothelial cells proteome response to an icMERS coronavirusMSV000080029 | PXD004719
Primary human microvascular endothelial cells Proteome response to an icMERS coronavirusMSV000081888
CoronaMassKB Hackathon: MassIVE/CCMS MSGF+ reanalysis of MSV000079703 / PXD004101, MSV000080029 / PXD004719, MSV000081888 Primary human microvascular endothelial cells Proteome response to an icMERS coronavirusRMSV000000322.2
CoronaMassKB Hackathon: Early-access community reanalysis of mass spectrometry data. MassIVE/CCMS MSGF+ reanalysis of MSV000079703 / PXD004101, MSV000080029 / PXD004719, MSV000081888 Primary human microvascular endothelial cells Proteome response to an icMERS coronavirus
+Homo sapiens (NCBITaxon:9606)
Middle East respiratory syndrome-related coronavirus (NCBITaxon:1335626)
Primary human fibroblasts proteome response to an icMERS coronavirusMSV000079701 | PXD004100
Primary human fibroblasts proteome response to an icMERS coronavirusMSV000080028 | PXD004718
Primary human fibroblasts Proteome response to an icMERS coronavirusMSV000081887
CoronaMassKB Hackathon: MassIVE/CCMS MSGF+ reanalysis of MSV000079701 / PXD004100, MSV000080028 / PXD004718, MSV000081887 Primary human fibroblasts proteome response to an icMERS coronavirusRMSV000000321.2
CoronaMassKB Hackathon: Early-access community reanalysis of mass spectrometry data. MassIVE/CCMS MSGF+ reanalysis of MSV000079701 / PXD004100, MSV000080028 / PXD004718, MSV000081887 Primary human fibroblasts proteome response to an icMERS coronavirus
+Homo sapiens (NCBITaxon:9606)
Middle East respiratory syndrome-related coronavirus (NCBITaxon:1335626)
Human Calu-3 cell proteome response to Middle Eastern Respiratory Syndrome (icMERS) coronavirusMSV000080025 | PXD004716
CoronaMassKB Hackathon: MassIVE/CCMS MSGF+ reanalysis of MSV000080025 / PXD004716 Human Calu-3 cell proteome response to Middle Eastern Respiratory Syndrome (icMERS) coronavirusRMSV000000319.2
CoronaMassKB Hackathon: Early-access community reanalysis of mass spectrometry data. MassIVE/CCMS MSGF+ reanalysis of MSV000080025 / PXD004716 Human Calu-3 cell proteome response to Middle Eastern Respiratory Syndrome (icMERS) coronavirus
+Homo sapiens (NCBITaxon:9606)
Middle East respiratory syndrome-related coronavirus (NCBITaxon:1335626)
Calu-3 cell proteome response to H1N1 virusMSV000080026
CoronaMassKB Hackathon: MassIVE/CCMS MSGF+ reanalysis of MSV000080026 Calu-3 cell proteome response to H1N1 virusRMSV000000317.2
CoronaMassKB Hackathon: Early-access community reanalysis of mass spectrometry data. MassIVE/CCMS MSGF+ reanalysis of MSV000080026 Calu-3 cell proteome response to H1N1 virus
+Homo sapiens (NCBITaxon:9606)
Influenza A virus (A/Wilson-Smith/1933(H1N1)) (NCBITaxon:381518)
A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-PurposingMSV000085144 | PXD018117
CoronaMassKB Hackathon: MassIVE/CCMS MSGF+ reanalysis of MSV000085144 / PXD018117 A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-PurposingRMSV000000316.2
CoronaMassKB Hackathon: Early-access community reanalysis of mass spectrometry data. MassIVE/CCMS MSGF+ reanalysis of MSV000085144 / PXD018117 A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Purposing
+Homo sapiens (NCBITaxon:9606)
Severe acute respiratory syndrome coronavirus 2 (NCBITaxon:2697049)
CoronaMassKB Hackathon: MassIVE/CCMS MSGF+ reanalysis of MSV000085096 / PXD017710 Proteome and Translatome of SARS-CoV-2 infected cellsRMSV000000315.2
CoronaMassKB Hackathon: Early-access community reanalysis of mass spectrometry data. MassIVE/CCMS MSGF+ reanalysis of MSV000085096 / PXD017710 Proteome and Translatome of SARS-CoV-2 infected cells
+Homo sapiens (NCBITaxon:9606)
Severe acute respiratory syndrome coronavirus 2 (NCBITaxon:2697049)